Center for Image Acquisition Facilities

The Center for Imaging Acquisition houses a Siemens Magnetom Prisma 3 Tesla MRI scanner and will house a Siemens Magnetom Terra 7 Tesla MRI scanner (slated for March 2017). These scanners are among the most advanced imaging devices approved for use on humans, and with them the CIA and related researchers push the boundaries of possibility in terms of spatial and temporal scans of the brain. Both foundational research and clinical scans are performed at the CIA, and the facility is equipped with knowledgeable staff and the latest in advanced equipment.

MRI Scanners

The Siemens Magnetom Prisma 3T MRI
The Prisma 3T is a high performance 3T MRI scanner based on the Trio system. It allows for unparalled simultaneous 80mT/m @ 200T/m/s gradients. Its 60 cm bore diameter allows for magnet homogeneity at 40 cm DSV – 0.2 ppm. With 64 – 128 channel receiving it is really the ultimate MRI scanner for neuroimaging. The Prisma offers as standard Diffusion Spectrum Imaging up to 514 diffusion directions allowing characterization of crossing fibers. It is also capable of higher resolution DTI with a reduced field of view – ZOOMit DTI for isotopic DTI. Higher SNR also allows for reproducible 3D ASL perfusion and improved resting state fMRI data.

The Magnetom Prisma is FDA-approved, which allows its high-resolution capabilities to be used in the clinical imaging of patients with neurological diseases and other conditions affecting the brain. The key part of this scanner which is unique are the powerful XR Gradients, which have a strength of 80 milliTesla per meter (mT/m) combined with a 200T-per-meter-per-second (T/m/s) slew rate. Furthermore, it employs advanced homogeneity and shimming functions for optimal MRI data acquisition.
3T Technical Specifications

Siemens Terra 7T MRI
The Siemens 7T is an actively shielded whole body highly homogeneous superconducting magnet. Delivery date is slated for March 2017. The 7T Terra system is designed for future clinical use with planned clinical clearances, and can be switched to clinical tasks with Dual Mode.

The system consists of an actively shielded highly homogeneous superconducting magnet (7.0 Tesla) housed in a 830 mm horizontal room temperature bore, low-loss helium cryostat and zero helium boil-off technology. Field shimming is primarily accomplished using superconducting shim coils. Final shimming is performed with a small number of passive shims. The system is supplied with a helium level monitor and an emergency quench heater control unit. A two-stage 4.2 K cryo refrigerator cooling system is employed, consisting of two independent cryocooler systems that eliminate the static cryogenic consumption.

Gradients & RF Receiver Technology
The gradient system essentially consists of a Gradient Power Amplifier (GPA) and a Gradient Coil (GC), both water cooled to sustain a high duty cycle. The Magnetom 7T uses the GPA model as is used on other Magnetom systems. The XR gradients are the same as the Prisma, capable of 80mT/m @ 200T/m/s gradients. The gradient coil includes the full set of 5 2nd order electrical shim coils to adjust B0 homogeneity for patient and each measurement volume. The Siemens RF receiver technology uses 64 channels, and the USC 7T includes a Nova Medical 32-channel head coil. The system also has an 8-channel parallel RF transmit array (pTx). 3rd order shims provide four out of the seven possible 3rd order shims built into the SC72 gradients, along with 2nd 4-fold SPS cabinet, wiring for 3rd order shim, electric infrastructure expansion, and an SW interface to drive additional 3rd order shims.

Other Equipment

The Center for Image acquisition has a variety of equipment to help you conduct a scan and ensure the comfort of your participants, from the latest in scanning technology to physiological monitoring equipment and emergency medical supplies. If you have questions about equipment that aren't answered here, please email cia@ini.usc.edu.

Patient/Participant Comfort
Private consultation rooms
Blankets & linens
Gowns & scrubs
Ear plugs
Blanket warming cabinet

Medical Equipment
Philips Healthcare Defibrillator with aspirator pump
MR-compatible oxygen tanks
MR-compatible transport stretcher
MR-compatible wheelchair
MR-compatible exam stool
MR-compatible IV stand
MR-compatible exam light
Pyxis MedStation

Physiological Monitoring
BioPac Systems MR Physiologic monitor - MP160 System - Ethernet-ready hardware and software solution for data acquisition and analysis, capable of recording up to 16 channels at once with different sampling rates and recording at speeds up to 400 kHz (aggregate). Respiration, SP02%, EDA, MRI trigger, Pulse and pulse rate manufacturer site for more information

Philips Invivo Expression MR400 Patient Monitor - Bedside-quality patient monitoring of anesthetic agents, body temperature, advanced cardiac architecture and superior ECG signal and wireless gating, position flexibility, F01 Basic setup (NBP,ECG,SpO2,CO2,RR), alarm flags, 15" LED widescreen viewing technical specifications

Console and Computer Equipment
The control rooms are equipped with iMacs capable of running Windows.
A Fuji PACS workstation is available to any physician with access to Keck’s PACS.

Stimulus Presentation
Visual presentation through Cambridge Research BOLDscreen 32 - 32-inch 1920x1080 widescreen LCD display, up to 16-bit RGB color control, 1400:1 contrast ratio and 120Hz panel drive with integrated calibration technical specifications

Siemens headphones for audio stimulus presentation are available but are only compatible with the 20-channel, not 32-channel, headcoil. Investigators may bring their own stimulus equipment as needed.

Noninvasive Neuromodulation
The Noninvasive Brain Stimulation (NIBS) Center is directly adjancent to the scanners and provides state-of-the-art equipment for neuronavigation-guided noninvasive brain stimulation (NIBS) including:

Frameless neuronavigation using a stereotactic image guidance system to facilitate positioning of the TMS coils over a subject's brain using MRI/fMRI (Rogue Research Brainsight™ Frameless system with mobile computer; https://www.rogue-research.com)

Single- and paired-pulse transcranial magnetic stimulation (TMS; Magstim BiStim2 composed of 2 linked 2002 units; http://www.magstim.com/product/20/magstim-bistim2)

Wireless, 8-channel transcranial electrical stimulation (tES) capable of transcranial direct current stimulation, transcranial alternating current stimulation (tACS), and transcranial random noise stimulation (tRNS) and simultaneous electroencephalography (EEG; Neuroelectrics StarStim8; http://www.neuroelectrics.com/products/starstim/starstim-8/)

Wireless, 4-channel surface electromyography (sEMG; Delsys Trigno Lab with 2 Trigno Standard Sensors and 2 Trigno Mini Sensors; http://www.delsys.com/products/wireless-emg/trigno-lab/)

Data acquisition software and hardware to synchronize TMS pulses with sEMG collection (CED micro1401; http://ced.co.uk/products/mic3in; CED Signal v. 6 software; http://ced.co.uk/products/sigovin )

Additional capabilities, including repetitive and theta-burst transcranial magnetic stimulation and simultaneous tES/fMRI, will be added in the future.